Cheat SheetMED

Vaccine Schedules Quick Reference

Overview of commonly administered vaccines including adult and pediatric schedules, storage requirements, and administration guidelines for pharmacy technicians.

Vaccine Schedules Quick Reference

Pharmacy technicians in many states can assist with or administer vaccines under pharmacist supervision. This cheat sheet covers vaccines commonly encountered in pharmacy practice, their general schedules, storage needs, and key facts for the CPHT exam.

Common Adult Vaccines

VaccineBrand Name(s)RouteSchedule (General Adult)Key Notes
Influenza (inactivated)Fluzone, Fluarix, othersIM1 dose annuallyGiven every fall/winter season. High-dose formulation available for adults 65+.
Influenza (live attenuated)FluMistIntranasal1 dose annuallyNot for immunocompromised patients or pregnant women.
COVID-19 (mRNA)Varies by manufacturerIMPer current CDC recommendationsSchedules and booster recommendations are updated regularly by the CDC.
Pneumococcal (PCV)Prevnar 20IMConsult current CDC schedule for age and risk-based recommendationsRecommended for adults 65+ and younger adults with certain risk factors.
Pneumococcal (PPSV)Pneumovax 23IM or SubQConsult current CDC scheduleMay be used in sequence with PCV per CDC guidance.
Shingles (recombinant)ShingrixIM2 doses, 2-6 months apartRecommended for adults 50+. Preferred over the older live vaccine.
Tdap / TdBoostrix, Adacel / TenivacIMTdap once, then Td booster every 10 yearsTdap given during each pregnancy (usually weeks 27-36). Td for wound management.
Hepatitis BEngerix-B, Heplisav-BIM2 or 3 dose series depending on productRecommended for all adults through age 59; age 60+ based on risk.
Hepatitis AHavrix, VaqtaIM2 doses, 6-12 months apartRecommended for travelers and those at risk.
HPVGardasil 9IM2 or 3 doses depending on age at initiationRoutinely given ages 11-12; catch-up through age 26.
MMRM-M-R IISubQ1 or 2 doses if no evidence of immunityLive vaccine. Contraindicated in pregnancy and severe immunodeficiency.
VaricellaVarivaxSubQ2 doses, 4-8 weeks apartLive vaccine. For adults without evidence of immunity.
RSV (adult)Arexvy, AbrysvoIMConsult current CDC recommendationsFor adults 60+ per shared clinical decision-making with provider.

Key Pediatric Vaccines (Overview)

VaccineAbbreviationGeneral Timing
Hepatitis BHepBBirth, 1-2 months, 6-18 months
RotavirusRV2, 4, (6) months depending on product
DTaPDTaP2, 4, 6, 15-18 months, 4-6 years
Haemophilus influenzae type bHib2, 4, (6), 12-15 months
Pneumococcal conjugatePCV2, 4, 6, 12-15 months
Inactivated poliovirusIPV2, 4, 6-18 months, 4-6 years
InfluenzaIIV or LAIVAnnually starting at 6 months
MMRMMR12-15 months, 4-6 years
VaricellaVAR12-15 months, 4-6 years
Hepatitis AHepA12-23 months (2 doses)

Vaccine Storage

Storage TypeTemperature RangeExamples
Refrigerated2-8 degrees C (36-46 degrees F)Most inactivated vaccines, Shingrix, Hep B
Frozen-50 to -15 degrees C (-58 to 5 degrees F)Varicella (Varivax), some COVID-19 formulations
Ultra-cold-90 to -60 degrees C (-130 to -76 degrees F)Certain mRNA COVID-19 vaccines (initial storage)

Vaccine Administration Key Points

  • IM injection sites: Deltoid (adults and older children) or vastus lateralis (infants and young children).
  • SubQ injection sites: Fatty tissue of the upper arm or thigh.
  • Needle gauge and length: IM typically uses 22-25 gauge, 1 to 1.5 inch needle for adults. SubQ uses 23-25 gauge, 5/8 inch needle.
  • Observation period: Patients should be monitored for at least 15 minutes after vaccination for signs of an allergic reaction.
  • Epinephrine must be readily available at all vaccination sites for treatment of anaphylaxis.
  • VIS (Vaccine Information Statement): Must be provided to the patient (or parent/guardian) before each vaccination, as required by federal law.
  • Documentation: Record the vaccine name, manufacturer, lot number, expiration date, dose, route, site, date administered, and name/title of the person administering.

Cold Chain Management

  • Use calibrated thermometers to monitor storage temperatures continuously.
  • Record temperatures at least twice daily (beginning and end of workday).
  • Do not store vaccines in the door of a refrigerator or freezer.
  • Keep vaccines in their original packaging until use.
  • Have a written emergency plan for temperature excursions (power outages, equipment failures).
  • Report temperature excursions to the immunization coordinator and follow manufacturer guidance on viability.

Exam Tips

  • Know the general route for each vaccine (IM vs. SubQ vs. intranasal).
  • Shingrix (shingles vaccine) is a 2-dose series and is NOT a live vaccine - this is commonly tested.
  • Live vaccines include MMR, varicella, LAIV (FluMist), and the oral rotavirus vaccine.
  • The VIS must be provided before every vaccination - this is a federal requirement.
  • Cold chain management and proper storage temperatures are frequently tested topics.

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